Research Shows Poultry Producers Can Gain Long-Term Wins With Inteprity

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Inteprity helps prevent mortality caused by necrotic enteritis with expanded feeding flexibility.

Necrotic enteritis (NE) is a constant concern in the poultry industry. In fact, it’s one of the most common and costly poultry diseases, with an estimated cost to the US poultry industry of $0.05 or more per bird.1 To help combat NE in flocks, poultry producers can implement Inteprity® from Elanco for extended feeding programs, which helps support healthier birds, healthier profitability and healthier choices. The first-in-class, animal-use-only, in-feed antibiotic has a variety of benefits, including reducing rotational frequency with multiple cycles.

Reduce Rotational Frequency With Multiple Cycles

New field trial research shows that poultry producers can use Inteprity for multiple cycles to prevent the mortality caused by NE and improve Intestinal Integrity (I2) scores without losing efficacy or risking resistance, compared to frequent rotations.

For instance:

  • Feeding Inteprity for multiple cycles (18 months) resulted in a steady I2 index score improvement.2
  • Inteprity fed for 9 months maintained I2 stability. 2
  • Frequently rotating Inteprity (every 4.5 months) showed a marked deterioration in I2 index score.2

Improve Key Lesion Scores With Continuous Use

The same data shows key lesion scores improved by using Inteprity for multiple cycles (18 months):

  • Mucus, cellular sloughing and feed passage incidence all decreased. 2
  • All other scores observed, including water content, NE and gizzard, remained stable and low. 2

“The evidence is clear,” said Bob Evans, Ph.D., D.V.M., A.C.P.V, Elanco Technical Consultant. “Using multiple cycles of Inteprity helps prevent the mortality caused by necrotic enteritis to improve Intestinal Integrity scores and key lesion scores compared to frequent rotations, without losing efficacy or risking resistance.”

By utilizing the innovation and flexibility of Inteprity, poultry producers can help keep their birds healthy while maximizing profitability. Producers can contact their Elanco technical consultant to discuss ways to reduce anticoccidial rotations using Inteprity, watch a recent webinar or visit Elanco.us/Inteprity.

Inteprity Usage Information:

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

Inteprity directions for use:

For the prevention of mortality caused by necrotic enteritis associated with Clostridium perfringens in broiler chickens:

  • Avilamycin is to be fed at 13.6 to 40.9 grams per ton of Type C medicated feed (15 to 45 ppm) as the sole ration for 21 consecutive days
  • Feed to chickens that are at risk of developing, but not yet showing clinical signs of necrotic enteritis associated with Clostridium perfringens

Inteprity Important Safety Information:

  • CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or on the order of a licensed veterinarian. To assure responsible antimicrobial drug use in broiler chickens, treatment administration must begin on or before 18 days of age. When using in combination with Maxiban, Monteban, Coban and BioCox, treatment and administration must begin on or before 18 days of age.
  • The safety of avilamycin has not been established in chickens intended for breeding purposes.
  • Avilamycin has not been demonstrated to be effective in broiler chickens showing clinical signs of necrotic enteritis prior to the start of medication.
  • The Veterinary Feed Directive (VFD) expiration date must not exceed 90 days from the date of issuance. VFDs for avilamycin shall not be refilled.

1 Elanco Animal Health. Data on file.

2 Elanco Animal Health. Data on file.